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Effects of Glucosamine on Joint Fluid in Osteoarthritis Patients

NCT01074476 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2016-06-29

No results posted yet for this study

Summary

Osteoarthritis (OA) is the most common joint disease associated with aging. Although many patients take glucosamine supplements as a non-traditional treatment for osteoarthritis, the effectiveness of these supplements is questionable. This study will evaluate glucosamine therapy by directly analyzing two functions of joint fluid that are impaired by osteoarthritis - namely, the abilities to lubricate the joint and absorb shocks during activity. Joint fluid samples will be collected from subjects with knee osteoarthritis and analyzed on a device that simulates typical joint movements. After 3 months of glucosamine supplementation, samples will be collected again to detect potential improvements in joint fluid function.

Conditions

Interventions

DIETARY_SUPPLEMENT

Glucosamine sulphate

750mg glucosamine sulphate (oral tablets), twice per day for 3 months

OTHER

Placebo

Placebo tablets, twice per day for 3 months

Sponsors & Collaborators

  • University of British Columbia

    lead OTHER

Principal Investigators

  • Ezra Kwok, Dr · University of British Columbia

  • Dana Grecov, Dr. · University of British Columbia

  • Christie Newton, Dr. · University of British Columbia

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
30 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-06-30
Primary Completion
2017-06-30
Completion
2017-06-30

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01074476 on ClinicalTrials.gov