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L-arginine for Knee Osteoarthritis Patients

NCT06054633 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 340

Last updated 2025-06-02

No results posted yet for this study

Summary

This study will examine the pain-relief efficacy and safety of L-arginine in knee OA patients.

Conditions

  • Osteoarthritis, Knee

Interventions

DIETARY_SUPPLEMENT

L-arginine tablet

L-arginine, 2 g, three times daily, for 12 weeks

DIETARY_SUPPLEMENT

Placebo tablet

Identical inert placebo, three times daily, for 12 weeks

Sponsors & Collaborators

  • Massachusetts General Hospital

    collaborator OTHER

  • School of Medicine, University of Nottingham

    collaborator UNKNOWN

  • Memorial University of Newfoundland

    collaborator OTHER

  • Xiangya Hospital of Central South University

    lead OTHER

Principal Investigators

  • Guanghua Lei, MD, PhD · Xiangya Hospital of Central South University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-03-20
Primary Completion
2025-09-30
Completion
2025-09-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06054633 on ClinicalTrials.gov