MedTrace Logo

Effect of Prebiotics on Function and Pain in Patients with Osteoarthritis and Obesity

NCT04172688 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 54

Last updated 2024-12-05

No results posted yet for this study

Summary

The purpose of the present study is to determine if prebiotic supplementation can, through changes in the intestinal gut microbiota, lead to improvements in knee function and physical performance and reduce knee pain in adults with obesity and idiopathic metabolic knee osteoarthritis. We hypothesize that prebiotics will reduce systemic and local (knee joint) inflammation, thus improving knee function, lower pain medication use, and enhance performance of daily life activities.

Conditions

Interventions

DIETARY_SUPPLEMENT

Prebiotic oligofructose-enriched inulin

Synergy1

DIETARY_SUPPLEMENT

Placebo maltodextrin

Equicaloric dose of maltodextrin

Sponsors & Collaborators

  • University of Calgary

    lead OTHER

Principal Investigators

  • Raylene A Reimer, PhD, RD · University of Calgary

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
30 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-11-18
Primary Completion
2021-10-01
Completion
2022-10-30

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04172688 on ClinicalTrials.gov