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Kinesiological / Dietary Supplement Intervention in Knee Osteoarthritis

NCT06269549 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 93

Last updated 2026-02-23

No results posted yet for this study

Summary

The goal of this clinical trial is to assess the effectiveness of dietary supplement combined with exercise in managing knee osteoarthritis (KOA). The main questions it aims to answer are:

* Is adding a dietary supplement to exercise additionally effective in managing KOA?
* Is adding exercise to the dietary supplement additionally effective in managing KOA?

Participants will be given in three groups:

1. Real dietary supplement alone
2. Real dietary supplement with exercise
3. Placebo dietary supplement with exercise

Investigators will compare groups 1 and 2, or 2 and 3, to answer the research questions.

The hypothesis is that participants who receive the dietary supplement along with exercise will experience greater reduction in pain level, improved physical function, and enhanced quality of life compared to those who receive a placebo combined with exercise or dietary supplement alone.

Conditions

  • Osteoarthritis, Knee

Interventions

OTHER

Non-training Real Dietary Supplement (G1)

One capsule of glucosamine three times daily, and one packet of hydrolyzed collagen.

OTHER

Training Placebo Dietary Supplement (G2)

One capsule of placebo glucosamine three times daily, and one packet containing placebo collagen + physical exercise (60 minutes per session twice a week)

OTHER

Training Real Dietary Supplement (G3)

One capsule of glucosamine three times daily, and one packet of hydrolyzed collagen + physical exercise (60 minutes per session twice a week)

Sponsors & Collaborators

  • Community Healthcare Center dr. Adolf Drolc Maribor (HCM)

    collaborator OTHER

  • University of Primorska

    lead OTHER

Principal Investigators

  • Nejc Šarabon, PhD · University of Primorska, Faculty of Health Sciences

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Model
FACTORIAL

Eligibility

Min Age
55 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-03-11
Primary Completion
2026-05-31
Completion
2026-06-30

Countries

  • Slovenia

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06269549 on ClinicalTrials.gov