Standard-PCNL vs Mini-PCNL vs Super-mini PCNL for the Treatment of ≥2 cm Renal Stone

Summary

Background: Standard-PCNL was considered as the first choice for ≥2 cm renal stones. Miniaturized technique Mini-PCNL has also been implicated in the past two decades. Recently, Super-mini PCNL (SMP) was introduced to treated ≤2.5cm renal stone. The miniaturized techniques seemed to take a longer operating time and have risk of getting infectious complications. However, there is no high quality of evidence showing that which kind of PCNL is best or what kind of patients is suitable for standard-PCNL, mini-PCNL or SMP.

Objective: To compare the efficacy and safety of Standard-PCNL (≥24Fr), Mini-PCNL (12-20Fr) and SMP(10-14Fr) for the treatment of ≥2 cm renal stones Study design: This study is a prospective, observational, international, multicenter registry cohort study Study population: All patients ≥14 years with ≥2 cm renal stone who are planned for Standard-PCNL, Mini-PCNL or SMP are eligible for this study.

Conditions

• Stone, Kidney
• Lithiasis Renal
• Surgery

Interventions

PROCEDURE

Standard-PCNL

percutaneous nephrostolithotomy (PCNL) with ≥24 Fr access tract for the treatment of ≥2 cm renal stone

PROCEDURE

Mini-PCNL

percutaneous nephrostolithotomy (PCNL) with 12-20 Fr access tract for the treatment of ≥2 cm renal stone

PROCEDURE

SMP

percutaneous nephrostolithotomy (PCNL) with 10-14 Fr access tract for the treatment of ≥2 cm renal stone

Sponsors & Collaborators

• Military Medical Academy, Bulgaria

  collaborator OTHER

• Massachusetts General Hospital

  collaborator OTHER

• Hospital de Clinicas José de San Martín

  collaborator OTHER

• Goldstadt Private Clinic

  collaborator UNKNOWN

• University College London Hospitals

  collaborator OTHER

• Hospital de Base do Distrito Federal

  collaborator UNKNOWN

• Mexican National Council of Urology

  collaborator UNKNOWN

• Vancouver General Hospital

  collaborator OTHER

• Lions Kidney Hospital and Urology Institute

  collaborator UNKNOWN

• Mt. Carmel Diocesan General Hospital

  collaborator UNKNOWN

• Clinical Emergency County Hospital

  collaborator UNKNOWN

• University of Belgrade

  collaborator OTHER

• Hospital das Clínicas, University of Sao Paulo Medical School

  collaborator UNKNOWN

• Vayodha and Venus International Hospitals

  collaborator UNKNOWN

• University Hospital of Vinalopo

  collaborator UNKNOWN

• Sismanoglio General Hospital

  collaborator OTHER

• New Mowasat Hospital

  collaborator UNKNOWN

• The First Affiliated Hospital of Guangzhou Medical University

  lead OTHER

Principal Investigators

• Guohua Zeng, PH.D & MD · The First Affiliated Hospital of Guangzhou Medical University

Eligibility

Min Age

14 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2019-01-01

Primary Completion

2021-01-01

Completion

2022-01-01