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Markers of Carnitine Acetyltransferase (CrAT) Protein Activity and Carnitine Availability

NCT03697928 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 13

Last updated 2020-10-19

No results posted yet for this study

Summary

This study aims to measure skeletal muscle metabolism in vivo during exercise using the non-invasive Magnetic Resonance Spectroscopy (MRS) technique. Specifically, phosphocreatine (PCr) kinetic and Acetylcarnitine levels will be determined at resting, during exercise and during the recovery post exercise. The target population is adult healthy men, with a wide range of maximal physical capacity.

Conditions

  • Metabolism and Nutrition Disorder
  • Metabolic Disturbance

Interventions

OTHER

Exercise metabolism

Participants will perform a series of exercises inside and outside the MRS/MRI scanner.

Sponsors & Collaborators

  • Maastricht University

    lead OTHER

Principal Investigators

  • Vera Schrauwen-Hinderling, Phd · Maastricht University

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-03-12
Primary Completion
2020-02-01
Completion
2020-02-01

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03697928 on ClinicalTrials.gov