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Mediterranean Diet, Exercise and Dementia Risk in UK Adults

NCT03673722 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 108

Last updated 2023-12-21

No results posted yet for this study

Summary

In cohort studies, a Mediterranean Dietary Pattern (MDP) has been consistently associated with reduced dementia incidence. The efficacy of a MDP to prevent dementia has never been directly demonstrated by RCTs, with existing research limited to cognition as a secondary outcome. Furthermore, despite their likely additive effects, the combined impact of Physical Activity (PA) and a MDP on dementia risk is unknown.

MedEx-UK is a RCT that will evaluate the feasibility of a multi-domain intervention to increase Mediterranean Dietary Pattern (MDP) adherence and physical activity (PA) in a group of older UK adults who are at above average risk of dementia.

Conditions

Interventions

OTHER

Foods consistent with a MDP

We aim to increase MDP by 3 points, according to a 14-point MEDAS score

OTHER

Physical Activity

We aim to increase PA to 150 minutes moderate activity per week.

OTHER

Control

Participants will be given generic healthy eating advice based

Sponsors & Collaborators

  • University of East Anglia

    lead OTHER

Principal Investigators

  • Anne Marie Minihane, PhD · University of East Anglia

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
55 Years
Max Age
74 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-04-01
Primary Completion
2021-02-26
Completion
2023-09-07

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03673722 on ClinicalTrials.gov