Intervention on Modifiable Lifestyle Risk Factors for Dementia Prevention

Summary

The overarching aim is to develop and deploy a multidomain intervention delivered on a mobile application to help older adults reduce their risk for dementia by improving a set of modifiable lifestyle risk factors associated with cognitive decline/dementia. The targeted domains are physical activity, diet, and cognitively stimulating activity. This registration concerns the Proof-of-concept study which will examine if individual parts of the intervention program achieve a clinically significant degree of change in the targeted behavioral risk outcomes. It is expected that following the program, at least 50% of participants will show evidence of a clinically significant degree of change in the behavioral risk outcome targeted by the intervention, when compared to baseline.

Conditions

• Risk Behavior
• Cognitive Decline

Interventions

BEHAVIORAL

Cognitive Engagement Group

Participants in this group will be encouraged to lead a cognitively stimulating lifestyle, as a means for cognitive decline/dementia risk reduction. This will be achieved by providing educational materials, practical tips and strategies, and suggestions about the different options to increase cognitively stimulating activities and by assisting participants outlining goals to progressively adopt a more cognitively active lifestyle.

BEHAVIORAL

Physical Activity Group

Participants in this group will be encouraged to lead a physically active lifestyle, as a means for cognitive decline/dementia risk reduction. This will be achieved by providing educational materials, practical tips and strategies, and suggestions about the different options to increase physical activities and by assisting participants outlining goals to progressively adopt a more physically active lifestyle.

BEHAVIORAL

Diet Group

Participants in this group will be encouraged to adopt a healthy diet, as a means for cognitive decline/dementia risk reduction. This will be achieved by providing educational materials, practical tips and strategies, and suggestions about the different options to change their diet and by assisting participants outlining goals to progressively adopt a Mediterranean-like diet.

BEHAVIORAL

Multimodal group

Participants assigned to this group will select which domain they wish to tackle first. Interventions are as described for the single-domain interventions.

Sponsors & Collaborators

• Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal

  collaborator OTHER

• Sojecci II Ltd

  collaborator UNKNOWN

• LuciLab

  lead INDUSTRY

Principal Investigators

• Sylvie Belleville, PhD · Centre de recherche de l'Institut Universitaire de gériatrie de Montréal

Study Design

Allocation

NON_RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

50 Years

Max Age

70 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2020-10-13

Primary Completion

2020-12-24

Completion

2021-01-15

Countries

• Canada

Study Locations