Computerized Cognitive Training for Patients With Epilepsy

Summary

This is a study on the effectiveness of computerized cognitive training for treatment of memory disorders in patients with epilepsy. Participants will be recruited from patients referred for neuropsychological assessment through the NYU Comprehensive Epilepsy Center's inpatient and outpatient services. Individuals meeting inclusion criteria will be screened for the presence of memory disturbance (defined by results of neuropsychological testing) and lack of exposure to any previous form of computerized cognitive training. All eligible subjects will be provided with an account for Lumosity with instructions to complete training modules 5 days per week for a total of 8 consecutive weeks. Outcomes will be evaluated through changes on the neuropsychological test battery.

Conditions

• Epilepsy

Interventions

BEHAVIORAL

Luminosity Trial Memory Match

Working memory task that has users indicate whether the current symbol matches the one presented 2 symbols previously. As the user makes correct responses, the previous symbols reduce in contrast and fade int the background, ultimately disappearing, forcing the user to rely entirely on working memory to achieve success

BEHAVIORAL

Luminosity Trial Memory Matrix

The purpose id to remember the location of squares on a grid

BEHAVIORAL

Luminosity Trial Famliar Faces

The purpose is to create associations between visual and verbal information

BEHAVIORAL

Luminosity Trial Brain Shift

The purpose is to decide whether or not cards with numbers and letters are either even or vowels. This measures inhibition, flexibility, and monitoring response set. Also, letterfluency, category fluency, and category switching.

BEHAVIORAL

Luminosity Trial Star Search

The purpose is to visually scan several different objects and find the different object in array of pictures. This measures selective attention.

BEHAVIORAL

Luminosity Trial Word Bubbles

The purpose is to decide what suffix to use in order to complete a word whena prefix is given. The subject needs to come up with he ending of three different prefixes to complete the word. This task measures verbal modality, deductive reasoning, integration of multiple bits of information, and flexibility of thinking.

BEHAVIORAL

Luminosity Trial Color Match

The purpose is to identify whether colors and words match each other. This measures the ability to inhibit a dominant and automatic verbal response

BEHAVIORAL

Luminosity Trial Ebb and Flow

Identify which direction leaves are pointing or moving depending on their color.This measures inhibition of impulsive and perseverative responding, and the ability to establish and maintain instructional set.

BEHAVIORAL

Luminosity TrialChalk Board Challenge

purpose is to problem solve quantitative reasoningequationsand to decide which card is greater or if the 2 cards are equal when the math problem is solved.

BEHAVIORAL

Luminosiuty Follow that Frog

The purposeis to remember the path a red frog takes as it jump from lilypad to lily pad in a pond. This measures flexibility of thinking on a visual-motor sequencing task and working memory

BEHAVIORAL

Luminosity Train of Thought

purpose is to guide specific colored trains into corresponding colored matching houses by attending to the different tracks. This measures divided attention.

Sponsors & Collaborators

• NYU Langone Health

  lead OTHER

Principal Investigators

• William Barr, MD · NYU Langone Health

Study Design

Allocation

NA

Purpose

TREATMENT

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Max Age

55 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2020-12-31

Primary Completion

2021-04-30

Completion

2021-04-30

Countries

• United States

Study Locations