Pilot Study of New Computer-based Neuropsychological Tool: Visual Tests, Touch Responses

Summary

This study is aimed at investigating three new tests that will form part of a computerized tool designed to test brain/cognitive functioning. The system will be evaluated along with the tests' usability on samples of healthy controls and neurologically impaired patient participants. These new tests will be assessed with regard to reliability and validity. Reliability will be addressed through investigation of internal consistency of the test items. Validity will be evaluated relative to traditional paper-and-pencil tests and differentiation between patient and healthy participants.Each participant will complete both the computerized and paper and pencil-based tests. The results will be analyzed to see how performances on the two test types compare. The overall aim of this project is to determine if these new computerized tasks are an improvement over standard paper and pencil-based neuropsychological measures.

Conditions

• Cerebral Neurological Illness

Interventions

DIAGNOSTIC_TEST

Railroad Test

This is a test designed to evaluate visual perception capacities and requires the participant to match photographs with railroads as a central theme. The participant is presented with a photograph image at the top of the screen and is asked to match it to one of the two, three or four choices in the lower portion of the display.

DIAGNOSTIC_TEST

Swamp Test

This is a test of immediate visual memory/attention for photographs with swamp wetlands as a central theme. The participant is briefly presented with a photograph which is replaced by two, three or four choices, one of which the participant is asked to select as the initially presented image.

DIAGNOSTIC_TEST

Presidents Recognition Test

This is a test of history knowledge and facial recognition using pictures of US presidents and non-president distractors. The participant is presented with two photographs and is asked to identify which is the picture of a US president

DIAGNOSTIC_TEST

Judgment of Line Orientation

This test requires participants to visually match the orientation of line segments. This is a test of visual perception and was included as a relative equivalent of the Railroad Test.

DIAGNOSTIC_TEST

Symbol Span subtest of the Wechsler Memory Scale-IV

This test requires participants to immediately recall a sequence of designs after a brief presentation. This is a test of immediate visual memory/attention and was included as a relative equivalent of the Swamp Test

DIAGNOSTIC_TEST

Information subtest of the Wechsler Adult Intelligence Scale-IV:

This test requires participants to answer factual knowledge questions. This is a test of fund of knowledge and was included as a verbal equivalent for the non-verbal Presidents Recognition Test.

DIAGNOSTIC_TEST

Digit Span subtest of the Wechsler Adult Intelligence Scale-I

This test requires the participant to repeat sets of digits forward, backward, and to sequence digits in ascending order. This is a test of immediate memory/attention and was included to investigate possible attentional correlates of the Swamp Test. This test includes a performance validity indicator that will permit analyses of validity indicators included with the experimental tests

DIAGNOSTIC_TEST

Reading subtest of the Wide Range Achievement Test

This test requires participants to read words printed on a card. This is a test of word knowledge/academic achievement and was included to investigate the academic achievement concomitants of the Presidents Recognition Test.

DIAGNOSTIC_TEST

Symbol Digit Modalities Test:

This test requires participants to visually match abstract symbols with numbers within a certain time period. The participant either verbalizes or writes the response on an answer sheet. This is a test of speed of information processing and was included to assess speed of response factors pertaining to all of the experimental tests as reflecting speed of information processing.

DIAGNOSTIC_TEST

Dot Counting Test

This test requires participants to count arrays of dots presented on a card while being timed. This is a performance validity test and was included to ascertain validity factors pertaining to each of the experimental tests.

Sponsors & Collaborators

• NYU Langone Health

  lead OTHER

Principal Investigators

• Alexander Chervinsky, PhD · NYU Langone Health

Study Design

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

21 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2019-05-10

Primary Completion

2023-12-06

Completion

2023-12-06

Countries

• United States

Study Locations