MedTrace Logo

Non-invasive Neurostimulation as a Tool for Diagnostics and Management for Neurodegenerative Diseases

NCT05326750 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 200

Last updated 2025-09-03

No results posted yet for this study

Summary

Double blinded, sham-controlled, randomized trial on repeated transcranial alternating current brain stimulation (tACS) in neurodegenerative diseases. The investigators will evaluate whether a 4-times daily repeated stimulation with gamma tACS on the posterior parietal cortex can improve symptoms in patients with neurodegenerative diseases, including dementia with Lewy Bodies, Alzheimer's disease, idiopathic normal pressure hydrocephalus and Frontotemporal dementia.

Conditions

  • Alzheimer Disease
  • Frontotemporal Dementia
  • Dementia With Lewy Bodies

Interventions

DEVICE

Gamma tACS (40 Hz) over the superior parietal cortex

Single session of gamma tACS (40 Hz) over the superior parietal cortex

Sponsors & Collaborators

  • Kuopio University Hospital

    lead OTHER

Principal Investigators

  • Eino Solje, MD, PhD · Kuopio University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-11-21
Primary Completion
2032-07-31
Completion
2032-07-31

Countries

  • Finland

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05326750 on ClinicalTrials.gov