PC-Based Cognitive Rehabilitation for Traumatic Brain Injury (TBI)

Summary

The investigators evaluated whether it was possible to improve the measurement of memory, attention, and executive function in patients who have suffered traumatic brain injury through the use of computer-based testing.

Note: the original design of the study was altered due to failure to recruit sufficient numbers of patients who were willing to undergo prolonged cognitive training.

Conditions

• Traumatic Brain Injury

Interventions

BEHAVIORAL

Digit span testing

Testing of short-term verbal memory with digit span

BEHAVIORAL

Spatial span testing

Testing of short-term visuospatial memory with spatial span.

BEHAVIORAL

Finger tapping

Testing motor speed with a finger tapping test.

BEHAVIORAL

Simple reaction time

Testing the time to respond to the appearance of a visual stimulus.

BEHAVIORAL

Choice reaction time

Testing the time needed to discriminate and respond to different visual stimuli.

BEHAVIORAL

Verbal fluency

Evaluating how many words are produced in 90s.

BEHAVIORAL

Verbal list learning

Evaluating short-term memory, learning, and memory interference in the recall of 12-word lists, presented three times. Evaluating long-term memory and recognition after a 20 min interval.

BEHAVIORAL

Trail making test

Evaluating visuomotor speed and executive function in Trail Making Tests, A and B. In the first, subjects connect successive numbers with the mouse. In the second, they connect numbers and letters in alternation.

BEHAVIORAL

Design fluency

Subjects create the maximal number of 4-line patterns in 90 s.

BEHAVIORAL

Questionnaire completion

Question completion time is measured on each question of the Post-Traumatic Stress Disorder check list (PCL) and on the cognitive failures questionnaire.

Sponsors & Collaborators

• US Department of Veterans Affairs

  lead FED

Principal Investigators

• David L. Woods, PhD · VA Northern California HCS

Eligibility

Min Age

18 Years

Max Age

78 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2009-07-31

Primary Completion

2013-03-31

Completion

2013-03-31