The American Cancer Society's 2026 statistics show a historic 70% 5-year relative survival rate for all cancers, up from 49% in the mid-1970s. Progress is attributed to earlier detection, targeted therapies, and immunotherapies, though disparities persist for American Indian and Alaska Native populations.
BioNTech presented phase 2 data for HER2-directed ADC Trastuzumab Pamirtecan showing 47.9% response rate in endometrial cancer, with FDA submission planned for 2026. BioLineRx dosed first patient in phase 1/2a GLIX1 trial for glioblastoma and reported new preclinical data. Both companies presented at ASCO 2026.
Anirban Maitra highlighted a talk at NYU Langone Health on milestones in developing RAS tricomplex inhibitors. The presentation also covered ongoing and planned combination approaches.
A large long-term NIH-funded trial found that older adults who practiced visual speed training were 25% less likely to develop Alzheimer's disease or other dementias even 20 years later, marking the first randomized clinical trial to assess such long-term links.
Researchers report advances in cancer treatment through three distinct approaches: repurposing a heart medication to target lymphoma enzymes, blocking stress proteins to enhance immunotherapy, and developing antibodies that restore immune system attacks on tumors.
Researchers discovered that lipocalin 2 (LCN2), a protein released by stressed cancer cells, helps lung and pancreatic tumors evade the immune system by manipulating macrophages and blocking T cell infiltration.
NYU Langone Health researchers discover pancreatic cancer cells toggle between rapid growth and chemotherapy resistance based on their proximity to extracellular matrix fibers, complicating single-drug treatment approaches.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07769918 |
Hypoxia-targeted Radiotherapy Boost for GBM |
NOT_YET_RECRUITING | NA |
| NCT07769905 |
Novel Irrigation Solution for Colonoscopy Visualization Pilot |
NOT_YET_RECRUITING | PHASE1 |
| NCT07767825 |
Pilot Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Fetuses With Severe CDH |
NOT_YET_RECRUITING | NA |
| NCT07767500 |
Stereotactic MR-Adaptive Radiation Therapy for Early-stage Renal Cancer |
RECRUITING | NA |
| NCT07752355 |
Young Onset Parkinson's Disease Subtypes and Pathogenic Mechanisms |
RECRUITING | |
| NCT07746674 |
Central Line-Associated Bloodstream Infection QI Project |
NOT_YET_RECRUITING | |
| NCT07746661 |
Behavioral Emergency Response Team (BERT) QI Project |
NOT_YET_RECRUITING | |
| NCT07746648 |
AI SNF Discharge Quality Improvement Project |
NOT_YET_RECRUITING | |
| NCT07744191 |
A Clinical Trial of Antiplatelets in Psoriasis |
NOT_YET_RECRUITING | PHASE4 |
| NCT07741357 |
Kidney RISE: Randomized Integrated Supportive CarE Trial |
NOT_YET_RECRUITING | NA |
