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Clinical Assessment of Arterial Dynamic Elastance in ICU Patients, Dependent on Inotropic or Vasopressor Drugs.

NCT03621618 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2025-11-18

No results posted yet for this study

Summary

The primary goal of the study is to determine Eadyn ( = PPV/SVV) as a functional measure of arterial load, in conjunction with other actual afterload indices, systemic vascular resistance and arterial elastance. A secondary aim is the assessment of the influences of vasopressors and inotropic drugs on Eadyn, as a parameter of ventriculo-arterial coupling.

Conditions

  • Sepsis
  • Cardiac Failure Acute

Interventions

DIAGNOSTIC_TEST

dobutamine

evaluation of effects of dobutamine on dynamic arterial elastance in cardiac failure

DIAGNOSTIC_TEST

norepinephrine

evaluation of effects of norepinephrine on dynamic arterial elastance in sepsis

Sponsors & Collaborators

  • Universitair Ziekenhuis Brussel

    lead OTHER

Principal Investigators

  • Jan Poelaert, PhD, MD · Universitair Ziekenhuis Brussel

  • Michel Vervoort, IR · Universitair Ziekenhuis Brussel

Study Design

Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
SEQUENTIAL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-03-31
Primary Completion
2023-06-02
Completion
2023-06-02

Countries

  • Belgium

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03621618 on ClinicalTrials.gov