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The Effects of Clonidine on the Diuretic Response in Cirrhotic Patients

NCT00356226 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 64

Last updated 2006-12-04

No results posted yet for this study

Summary

To examine the effects of the addition of clonidine to diuretics on the mobilization of ascites at short-term (diuretic response and requirement of diuretics) and long-term (readmissions for tense ascites and requirement of diuretics) in cirrhotics with increased sympathetic nervous system. Secondary objectives were to study neuro-hormonal,hemodynamic effects and side effects of clonidine and diuretics.

Conditions

  • Ascitic Cirrhosis
  • Hyperactivation of Sympathetic Nervous System

Interventions

DRUG

clonidine

Sponsors & Collaborators

  • CHU de Charleroi

    lead OTHER

Principal Investigators

  • Lenaerts Anne, MD · ISPPC CHU de Charleroi

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
FACTORIAL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2000-10-31

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00356226 on ClinicalTrials.gov