The Haem and Nitrite Study - The Effects of Haemoglobin NO-blockade on Nitrite-induced Forearm Vessel Dilatation
NCT03077763 · Status: UNKNOWN · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 41
Last updated 2017-03-20
Summary
The study is a pharmacodynamic random order cross-over trial investigating the physiological effects of intra-arterial infusion of nitrite following a haemolysed autologous blood transfusion.
Conditions
- Healthy Volunteers
Interventions
- DRUG
-
Sodium Nitrite
Sponsors & Collaborators
-
University of East Anglia
lead OTHER
Principal Investigators
-
Michael P Frenneaux, FRCP, FESC · Dean of Medicine, Norwich Medical School, The University of East Anglia, UK
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-12-31
- Primary Completion
- 2018-03-31
- Completion
- 2018-03-31
Countries
- United Kingdom
Study Locations
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