Heart and Blood Pressure Study: The Effect of Aortic Impedance on Myocardial Relaxation
NCT00204984 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 17
Last updated 2019-02-08
Summary
Does dilation of blood vessels (vasodilation), which decreases aortic stiffness, have a greater effect on heart myocardium relaxation (diastole) than vasodilation which affects mean pressure equally without improving aortic stiffness?
Conditions
Interventions
- DRUG
-
oral hydralazine and intravenous nesiritide
vasodilators
Sponsors & Collaborators
-
Scios, Inc.
collaborator INDUSTRY -
University of Wisconsin, Madison
lead OTHER
Principal Investigators
-
Nancy K Sweitzer, MD, PhD · University of Wisconsin, Madison
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2005-05-31
- Primary Completion
- 2006-12-20
- Completion
- 2006-12-20
Countries
- United States
Study Locations
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