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Cannabis Use and Epigenetic Alterations in Human Male Sperm Cells

NCT03614637 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 42

Last updated 2020-07-07

No results posted yet for this study

Summary

This is a follow-up project to a proof-of-concept study to determine if Cannabis use in male humans is associated with changes in deoxyribonucleic acid (DNA) methylation profile of sperm. This proposal will examine the epigenome of sperm from men actively using Cannabis before and after a period of Cannabis abstinence. The results will be compared to control non-users.

Conditions

  • Cannabis Use

Interventions

OTHER

Cannabis use abstinence for 11 weeks

Cannabis user group will be asked to abstain from any form of Cannabis use for 11 weeks. During their contingency management phase/abstinence phase, they will be required to come to the clinic for 25 visits over an 11 week period of abstinence.

Sponsors & Collaborators

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-11-07
Primary Completion
2020-03-16
Completion
2020-03-16

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03614637 on ClinicalTrials.gov