Identification and Characterization of the Methylation Abnormalities on Whole Genome Among Infertile Men

NCT01239186 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 49

Last updated 2013-08-07

No results posted yet for this study

Summary

This study will analyse the sperm global methylation status of 62 infertile men before assisted reproductive techniques. Some of these patients (20%) present hypomethylation of H19 locus. A global methylation analysis may reveal others imprinting defects.

Conditions

  • Oligospermia

Interventions

OTHER

methylation analyses on spermatozoa from infertile men

microarray analysis(www.EPIGENOMICS.com)

Sponsors & Collaborators

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • Célia Ravel, MD · TENON Hospital - APHP

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-06-30
Primary Completion
2011-09-30
Completion
2012-12-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01239186 on ClinicalTrials.gov