Identification and Characterization of the Methylation Abnormalities on Whole Genome Among Infertile Men
NCT01239186 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 49
Last updated 2013-08-07
Summary
This study will analyse the sperm global methylation status of 62 infertile men before assisted reproductive techniques. Some of these patients (20%) present hypomethylation of H19 locus. A global methylation analysis may reveal others imprinting defects.
Conditions
- Oligospermia
Interventions
- OTHER
-
methylation analyses on spermatozoa from infertile men
microarray analysis(www.EPIGENOMICS.com)
Sponsors & Collaborators
-
Assistance Publique - Hôpitaux de Paris
lead OTHER
Principal Investigators
-
Célia Ravel, MD · TENON Hospital - APHP
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- MALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2009-06-30
- Primary Completion
- 2011-09-30
- Completion
- 2012-12-31
Countries
- France
Study Locations
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