Effects of Xanthohumol on Metabolic Syndrome Progression
NCT03561116 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 76
Last updated 2018-06-19
Summary
A huge body of scientific evidence has suggested that xanthohumol (XAN) consumption, a polyphenol present in beer, has a positive effect on energy metabolism. This compound is known for its antioxidant, anti-inflammatory and anti-cancer properties which confer potential to be used as a food supplement. Nevertheless, XAN lipophilic properties prevent the extensive use of this molecule as a functional food compound. The company TA-XAN S.A.M. (Wiesbaden, Germany) has patented a method to overcome this solubility problem. So, the main aim of this study is to evaluate the effects of XAN consumption on metabolic syndrome progression in individuals recently diagnosed.
Conditions
- Metabolic Syndrome
Interventions
- DIETARY_SUPPLEMENT
-
XAN
Daily intake of a sachet containing 12 mg of XAN
- DIETARY_SUPPLEMENT
-
Placebo
Daily intake of a sachet containing excipient
Sponsors & Collaborators
-
Universidade do Porto
lead OTHER
Principal Investigators
-
Raquel Soares, PhD · Medical Faculty of University of Porto
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 25 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-05-19
- Primary Completion
- 2018-09-30
- Completion
- 2018-10-31
Countries
- Portugal
Study Locations
More Related Trials
-
Polyphenols and Endothelial Function
NCT00619749 ·Status: TERMINATED ·Phase: PHASE3
-
Epigallocatechin Gallate Lowers Circulating Catecholamine Concentrations and Alters Lipid Metabolism.
NCT03199430 ·Status: COMPLETED ·Phase: PHASE4
-
Acute Dose-ranging Effects of Mango Leaf Extract (Zynamite® 15%) on Cognitive Function and Cerebral Blood Flow
NCT05580146 ·Status: COMPLETED ·Phase: NA
-
Flavonoids, Blood Pressure and Blood Vessel Function
NCT01530893 ·Status: COMPLETED ·Phase: NA
-
Effect of Resveratrol on Age-related Insulin Resistance and Inflammation in Humans
NCT01354977 ·Status: COMPLETED ·Phase: PHASE2
-
The Effects of a Polyphenol-enriched Fruit Drink on Metabolic Health
NCT01706653 ·Status: COMPLETED ·Phase: NA
-
ENDOCUR - Modulation of Endotoxaemia Via Curcumin Intake in Healthy Overweight Adults
NCT03329781 ·Status: COMPLETED ·Phase: NA
-
Effects of Berries and Vegetables on Cardiometabolic Risk Markers and Cognitive Functions
NCT01562392 ·Status: COMPLETED ·Phase: NA
-
The Absorption and Metabolism of Seaweed Polyphenols in Humans
NCT02496806 ·Status: COMPLETED ·Phase: NA
-
The Effects of a Polyphenol-enriched Fruit Drink on Metabolic Health(2)
NCT01836887 ·Status: COMPLETED ·Phase: NA
-
Effects on Cognitive Functions and Mood of Food Products Rich in Polyphenols
NCT02243956 ·Status: COMPLETED ·Phase: NA
-
Anthocyanin Dose-escalation Study in Healthy Young Adults
NCT02760511 ·Status: COMPLETED ·Phase: NA
-
Evaluation of New Beverages Rich in Bioactive Compounds for the Modulation of Energetic Metabolism in Overweight Adults
NCT04016337 ·Status: COMPLETED ·Phase: NA
-
Effects of Xoçai Antioxidant Supplements on Atherosclerosis Risk Factors
NCT00666250 ·Status: COMPLETED ·Phase: NA
-
Absorption of Phenolic Acids From Coffee in Humans
NCT01912144 ·Status: COMPLETED ·Phase: NA
-
Effect of Polyphenol Extract on Cardiovascular Health Markers: a 4 Way Randomised Crossover Study
NCT05220059 ·Status: UNKNOWN ·Phase: NA
-
Aronia Berry Consumption on Vascular Function
NCT03041961 ·Status: COMPLETED ·Phase: NA
-
Cranberry (Poly)Phenol Consumption on Vascular Function
NCT02764749 ·Status: COMPLETED ·Phase: NA
-
Absorption and Antioxidant Effects of Polyphenolics From Acai
NCT02227628 ·Status: COMPLETED ·Phase: NA
-
Cardiovascular Benefits of Acai Polyphenols in Volunteers at Risk of Metabolic Syndrome
NCT02292329 ·Status: COMPLETED ·Phase: NA
-
Study of the Effects of Plx on Bioparametric Measurements.
NCT05128812 ·Status: COMPLETED ·Phase: NA
-
Investigation of the Acute and Chronic Cognitive and Mood Effects of CP9700 in Humans
NCT03526406 ·Status: COMPLETED ·Phase: NA
-
The Effects of Plant Bioactives on Platelet Function
NCT01130129 ·Status: COMPLETED ·Phase: NA
-
Effects of Oral Fruit Concentrate Supplementation on Cardiometabolic Parameters.
NCT04177238 ·Status: COMPLETED ·Phase: NA
-
Plasma-Induced Changes in the Metabolome Following Polyphenol Consumption
NCT06144489 ·Status: COMPLETED ·Phase: NA