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The Liver Health Study for Patients with NAFLD

NCT03151798 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 336

Last updated 2024-12-19

No results posted yet for this study

Summary

The study will investigate whether the level of fat stored in the liver is related to the liver's ability to burn fat.

Conditions

Interventions

BEHAVIORAL

Phase II: Lifestyle treatment

Subjects will undergo energy restriction and exercise training over a 9 month period.

BEHAVIORAL

Phase II: Control treatment

Subjects will receive dietary advice and receive information on a stretching program.

OTHER

Phase I: Observational studies

The liver samples from patients undergoing bariatric surgery or a diagnostic liver biopsy will undergo in vitro assays to determine the capacity of the tissue to burn fat

Sponsors & Collaborators

  • University of Missouri-Columbia

    lead OTHER

Principal Investigators

  • Elizabeth Parks, PhD · University of Missouri-Columbia

  • Jamal Ibdah, MD · University of Missouri-Columbia

  • Scott Rector, PhD · University of Missouri-Columbia

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
SINGLE_GROUP

Eligibility

Min Age
22 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-08-09
Primary Completion
2022-03-03
Completion
2023-04-29

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03151798 on ClinicalTrials.gov