Exercise, Arterial Cross-Talk Modulation and Inflammation in an Ageing Population
NCT02796976 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 158
Last updated 2018-12-06
Summary
The aims of the study are twofold. In the cross-sectional approach (Part I), the study will be conducted in an older population to assess the association of physical fitness on different parts of the human vascular bed. In the interventional approach (Part II), it aims to investigate whether and to what extent advanced vascular ageing (AVA) in older subjects with increased cardiovascular risk can be reversed by regular walking- based high intensity interval training.
Conditions
- Cardiovascular Disease
- Obesity
- Atherosclerosis
- Heart; Disease, Activity
Interventions
- OTHER
-
Training or control condition
Participants get a 12 week high intensity and walking-based interval training which is adapted to their individual physical fitness level or a general recommendation on physical activity according to European Guidelines.
Sponsors & Collaborators
-
University Hospital, Basel, Switzerland
collaborator OTHER -
Basel Institute of Clinical Epidemiology (BICE)
collaborator OTHER -
University of Basel
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 50 Years
- Max Age
- 79 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-03-31
- Primary Completion
- 2017-12-31
- Completion
- 2018-02-28
Countries
- Switzerland
Study Locations
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