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Feasibility of Aerobic Exercise With Blood Flow Restriction Training in People Living With Type 2 Diabetes

NCT07196371 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2026-01-26

No results posted yet for this study

Summary

The goal of this trial is to learn if blood flow restriction training with treadmill walking is possible for individuals living with type 2 diabetes. It will also learn about how the blood flow restriction with treadmill walking could improve health.

The main questions it aims to answer are:

Is 6 weeks of treadmill walking with blood flow restriction reasonable for people with type 2 diabetes to perform? Does treadmill walking with blood flow restriction training help manage type 2 diabetes better than just treadmill walking?

Researchers will compare treadmill walking with blood flow restriction to treadmill walking without blood flow restriction to see if blood flow restriction works to manage type 2 diabetes based on fitness and blood sugar levels.

Participants will:

Perform treadmill walking with or without blood flow restriction for 96 minutes a week for 6 weeks.

Visit the lab before and after the exercise for tests and questionnaires.

Conditions

Interventions

BEHAVIORAL

Aerobic Training with Blood Flow Restriction

Participants will undergo a 6-week aerobic training intervention with blood flow restriction applied to the lower limbs. Blood flow restriction will be applied using a blood pressure cuff set between 60-80% of limb arterial occlusion pressure. Training will consist of treadmill walking at 40-50% of heart rate reserve (HRR) for 32 minutes per session, 3 times per week for a total of 96 minutes per week.

BEHAVIORAL

Standard Aerobic Training

Participants will follow the same aerobic training protocol as the AT+BFR group but without blood flow restriction. Training will consist of treadmill walking at 40-50% of HRR for 32 minutes per session, 3 times per week for a total of 96 minutes per week.

Sponsors & Collaborators

  • Diabetes Canada

    collaborator OTHER

  • University of Guelph

    collaborator OTHER

  • University of British Columbia

    collaborator OTHER

  • University of New Brunswick

    lead OTHER

Principal Investigators

  • Martin Senechal, PhD · Cardiometabolic Exercise & Lifestyle Laboratory, Fredericton, New Brunswick

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
19 Years
Max Age
64 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-01-01
Primary Completion
2028-12-31
Completion
2028-12-31

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07196371 on ClinicalTrials.gov