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Influence of a Multi-parametric Optimization Strategy for General Anesthesia on Postoperative Morbidity and Mortality

NCT02668250 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 2495

Last updated 2021-08-26

No results posted yet for this study

Summary

With the increasing aging population demographics and life expectancies, the number of very elderly patients undergoing surgery is rising. Elderly patients constitute an increasingly large proportion of the high-risk surgical group.

Cardiac complications and postoperative pulmonary complications are equally prevalent and contribute similarly to morbidity, mortality, and length of hospital stay. Specific optimization strategy of general anesthesia has been tested in high-risk patients undergoing major surgery to improve outcomes.

Our hypothesis is that a combined optimization strategy of anesthesia concerning hemodynamic, ventilation, and depth of anesthesia may improve short- and long- term outcome in elderly undergoing high risk surgery.

Conditions

  • Coronary; Ischemic
  • Arrhythmias, Cardiac
  • Heart Failure
  • Peripheral Vascular Diseases
  • Dementia
  • Stroke
  • Pulmonary Disease, Chronic Obstructive
  • Respiratory Insufficiency
  • Alcoholism
  • Cancer
  • Diabetes
  • Renal Insufficiency

Interventions

PROCEDURE

OPTI-AGED

OPTI-AGED is composed of a multi-parametric optimization strategy.

PROCEDURE

Usual Care

Patients receive the usual care.

Sponsors & Collaborators

  • Ministry of Health, France

    collaborator OTHER_GOV

  • Centre Hospitalier Universitaire de Saint Etienne

    lead OTHER

Principal Investigators

  • MOLLIEX Serge, MD · CHU SAINT-ETIENNE

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-02-03
Primary Completion
2020-02-05
Completion
2021-03-16

Countries

  • France

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02668250 on ClinicalTrials.gov