Associations of Postoperative Delirium With Perioperative Frailty Worsening and Their Combined Effect on 1-Year Mortality in Older Surgical Patients
NCT07259850 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 6196
Last updated 2025-12-09
Summary
Postoperative delirium (POD) is a frequent complication in older surgical patients and is associated with adverse outcomes, while frailty is also highly prevalent during the perioperative period. This study aimed to determine whether POD accelerates perioperative frailty worsening and to assess the effect of their coexistence on 1-year mortality.
Conditions
- Postoperative Delirium (POD)
- Frailty at Older Adults
- Mortality
- Recovery of Function
Sponsors & Collaborators
-
Chinese PLA General Hospital
lead OTHER
Eligibility
- Min Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-04-01
- Primary Completion
- 2022-04-30
- Completion
- 2023-04-30
Countries
- China
Study Locations
More Related Trials
-
The Effect of Early Postoperative Pain on Postoperative Delirium (POD) in Elderly Patients Undergoing Abdominal Surgery
NCT06964893 ·Status: COMPLETED
-
Incidence and Risk Factors of PostopeRativE Delirium in ICU in China
NCT03704324 ·Status: UNKNOWN
-
Preoperative Lymphocyte-to-Monocyte Ratio and Postoperative Delirium by Frailty Status in Older Surgical Patients
NCT07322744 ·Status: COMPLETED
-
Anesthesia-analgesia Methods and Postoperative Delirium
NCT01661907 ·Status: COMPLETED ·Phase: NA
-
The Neuro-epigenetics Biomarkers of Postoperative Delirium in Elderly Patients Undergoing Hip/Knee Replacement
NCT04923243 ·Status: UNKNOWN
-
Association Between Preoperative Health and Functional Status and Postoperative Complications in Elderly Patients
NCT07259837 ·Status: COMPLETED
-
Postoperative Frailty Trajectories and One-Year Mortality in Older Surgical Patients
NCT07322809 ·Status: COMPLETED
-
A Predictive Study of Peripheral Blood Biomarkers on Postoperative Neurocognitive Dysfunction in Elderly Frail and Non-frail Patients Undergoing Gastrointestinal Surgery
NCT06334289 ·Status: NOT_YET_RECRUITING
-
Incidence, Long- Term Outcome and Factor Related to Non- Cardiac Postoperative Delirium in Elderly Patients
NCT02131181 ·Status: COMPLETED
-
Postoperative Delirium in Cardiac Surgery ICU
NCT04527341 ·Status: UNKNOWN
-
Low-dose Neuroleptanalgesia for Postoperative Delirium in Elderly Patients
NCT05068180 ·Status: UNKNOWN ·Phase: PHASE4
-
Different Frailty Scores to Incidence of Post-operative Delirium and Cognitive Dysfunction
NCT04056871 ·Status: COMPLETED
-
Effect of Preoperative Anxiety on Postoperative Delirium in Elderly Patients Undergoing Orthopaedic Surgery.
NCT04216615 ·Status: UNKNOWN
-
Correlation Analysis of POD and pNCD in Elderly Spinal Surgery Patients
NCT06466083 ·Status: RECRUITING
-
INcidence of PostOperative Delirium Incidence in Surgical Patients: an Observational Cohort Study in New Zealand
NCT04840316 ·Status: UNKNOWN
-
Postoperative Delirium and Its Biomarkers in Elderly Patients Undergoing Non-cardiac and Non-neurosurgery.
NCT05177159 ·Status: UNKNOWN
-
Association of Frailty and Delirium in Elderly Hip Fracture Patients
NCT05246254 ·Status: UNKNOWN
-
Postoperative Delirium in the Post-anesthesia Care Unit
NCT06318364 ·Status: RECRUITING
-
The Effect of Frailty to Perioperative Complications in the Elderly
NCT04120012 ·Status: COMPLETED
-
Correlation Between Perioperative EEG Features and Delirium After General Anesthesia
NCT06082024 ·Status: RECRUITING
-
Preoperative Frailty and Postoperative Prognosis in the Elderly After Major Surgeries
NCT04655651 ·Status: COMPLETED
-
Relationship Between Perioperative Sleep Disturbance and Postoperative Delirium
NCT05457387 ·Status: COMPLETED
-
Intraoperative Sedation and Postoperative Delirium
NCT02573558 ·Status: COMPLETED
-
The Impact of Smoking on the Prognosis of Elderly Surgical Patients
NCT06392308 ·Status: NOT_YET_RECRUITING
-
Incidence and Perioperative Factors Associated With Postoperative Delirium
NCT02904928 ·Status: COMPLETED