Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART133
NCT02541370 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2019-12-17
Summary
RATIONALE: Placing a tumor antigen chimeric receptor that has been created in the laboratory into patient autologous or donor-derived T cells may make the body build immune response to kill cancer cells.
PURPOSE: This clinical trial is studying genetically engineered lymphocyte therapy in treating patients with Relapsed and/or Chemotherapy Refractory Advanced Malignancies.
Conditions
- Liver Cancer
- Pancreatic Cancer
- Brain Tumor
- Breast Cancer
- Ovarian Tumor
- Colorectal Cancer
- Acute Myeloid and Lymphoid Leukemias
Interventions
- BIOLOGICAL
-
anti-CD133-CAR vector-transduced T cells
genetically engineered lymphocyte therapy
Sponsors & Collaborators
-
Chinese PLA General Hospital
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-06-30
- Primary Completion
- 2019-06-30
- Completion
- 2019-06-30
Countries
- China
Study Locations
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