A Study of CAR-T Cells Therapy for Patients With Relapsed and/or Refractory Central Nervous System Hematological Malignancies
NCT04532203 · Status: RECRUITING · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 72
Last updated 2020-10-26
Summary
A Study of CAR-T Cells Therapy for Patients With Relapsed and/or Refractory Central Nervous System Hematological Malignancies
Conditions
- Acute Lymphoblastic Leukemia
- Non-Hodgkin's Lymphoma
Interventions
- DRUG
-
CAR-T cells
Each subject receive CAR T-cells by intravenous infusion
- PROCEDURE
-
Ommaya Reservoir
Surgical catheter placement into the fourth ventricle of the brain
Sponsors & Collaborators
-
Zhejiang University
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 3 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-11-01
- Primary Completion
- 2023-11-01
- Completion
- 2026-11-01
Countries
- China
Study Locations
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