CD123-Targeted CAR-T Cell Therapy for Relapsed/Refractory Acute Myeloid Leukemia
NCT04265963 · Status: UNKNOWN · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 45
Last updated 2023-04-18
Summary
There are limited options for treatment of relapse/refractory acute myeloid leukemia (AML). CD123 CAR-T cells may have an attractive and permanent effect on anti-tumor. This study purpose to estimate the safety and efficiency of CD123 CAR-T cells to patients with relapse/refractory AML.
Conditions
- Leukemia
- Leukemia, Myeloid
- Leukemia, Myeloid, Acute
Interventions
- BIOLOGICAL
-
CD123 CAR-T cells
CD123 CAR-T cell therapy
Sponsors & Collaborators
-
Chongqing Precision Biotech Co., Ltd
lead INDUSTRY
Principal Investigators
-
Sanbin Wang, MD · 920th Hospital of Joint Logistics Support Force of People's Liberation Army of China
-
Cheng Qian, PhD · Chongqing University Cancer Hospital
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 2 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-09-01
- Primary Completion
- 2023-12-31
- Completion
- 2024-07-01
Countries
- China
Study Locations
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