Clinical Study on Safety and Efficacy of Anti-CLL1 /+CD33 CAR T Cells in the Treatment of Acute Myeloid Leukemia
NCT05943314 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL
Last updated 2023-11-02
Summary
This is a single-center, single-arm, open, intravenous drug administration of the safety and efficacy of clinical study.
Conditions
Interventions
- BIOLOGICAL
-
CLL1/+CD33 CAR-T
CLL1/+CD33 CAR T is a type of CAR T cell therapy for patients with treating/relapsed acute myeloid leukemia.
Sponsors & Collaborators
-
Guangzhou Bio-gene Technology Co., Ltd
lead INDUSTRY
Principal Investigators
-
Hui Zhang, doctor · Children's Hospital of Fujian Province
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 1 Year
- Max Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-07-12
- Primary Completion
- 2023-08-28
- Completion
- 2023-08-28
Countries
- China
Study Locations
More Related Trials
-
Anti-CLL1 CAR T-cell Therapy in CLL1 Positive Relapsed/Refractory Acute Myeloid Leukemia (AML)
NCT04884984 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Treatment of Relapsed and/or Chemotherapy Refractory CD33 Positive Acute Myeloid Leukemia by CART-33
NCT01864902 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Evaluate the Safety and Efficacy of CLL1+CD33 CAR-T in Patients With R/R AML
NCT05467254 ·Status: UNKNOWN ·Phase: PHASE1
-
Anti-CD33 CAR-T Cells for the Treatment of Relapsed/Refractory CD33+ Acute Myeloid Leukemia
NCT05445765 ·Status: UNKNOWN ·Phase: PHASE1
-
Study to Evaluate the Safety and Preliminary Efficacy of CLL1 and CD38 Dual CAR-T in r/r AML
NCT06110208 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART133
NCT02541370 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Phase I/II Study of Enhanced CD33 CAR T Cells in Subjects With Relapsed or Refractory Acute Myeloid Leukemia
NCT04835519 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Evaluate the Safety and Efficacy of CLL1 CAR-T in Patients With R/R AML
NCT05467202 ·Status: UNKNOWN ·Phase: PHASE1
-
CD33-CAR T Cell Therapy for the Treatment of Recurrent or Refractory Acute Myeloid Leukemia
NCT05672147 ·Status: RECRUITING ·Phase: PHASE1
-
Multiple CAR-T Cell Therapy Targeting AML
NCT04010877 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Clinical Study of Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of Myeloid Leukemia
NCT04923919 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
a Study of CT0596 in Relapsed/Refractory Multiple Myeloma and Relapsed/Refractory Plasma Cell Leukemia
NCT06718270 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Clinical Study of CLL-1 CAR-T in the Treatment of Children With R/R AML
NCT07338357 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1
-
A Study of CT0596 in Relapsed/Refractory Multiple Myeloma and Relapsed/ Refractory Plasma Cell Leukemia
NCT06730256 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Safety and Efficacy of CLL1 CAR-T Followed by Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia
NCT07342244 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Multi-centers, Open-Label, Phase 2 Study to Evaluate the Efficacy and Safety of Donor-Derived CD7 CAR T Cells in Subjects With Relapsed or Refractory T-cell Leukemia/Lymphoma
NCT04689659 ·Status: COMPLETED ·Phase: PHASE2
-
CD123-Targeted CAR-T Cell Therapy for Relapsed/Refractory Acute Myeloid Leukemia
NCT04265963 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Clinical Study of Anti-CD1a CAR-T in the Treatment of R/R Acute T-lymphoblastic Leukemia/Lymphoblastic Lymphoma
NCT05745181 ·Status: RECRUITING ·Phase: PHASE2
-
Safety and Efficacy of Anti-CD20/CD30 CAR-T Cells in Subjects with Relapsed/Refractory Lymphoma
NCT06532643 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Anti-CD30 CAR-T Therapy in Patients With Refractory/Relapsed Lymphocyte Malignancies
NCT04008394 ·Status: UNKNOWN ·Phase: PHASE1
-
Anti-CD33 CAR NK Cells in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia
NCT05008575 ·Status: UNKNOWN ·Phase: PHASE1
-
Safety and Efficacy of CD123-Targeted CAR-T Therapy for Relapsed/Refractory Acute Myeloid Leukemia
NCT04272125 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
CD70 Targeted CAR-T Cells in CD70 Positive Relapsed/Refractory Lymphoma
NCT05948033 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
EX02 CAR-T Cells for Relapsed and Refractory Acute Myeloid Leukemia
NCT06642025 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Donor-derived CAR-T Cells in the Treatment of AML Patients
NCT04766840 ·Status: UNKNOWN ·Phase: PHASE1