Natural History of Spinal Muscular Atrophy Type 1 in Taiwan

Summary

Spinal muscular atrophy (SMA) is an autosomal recessive disorder characterized by degeneration of motor neurons in the spinal cord and caused by mutations of the survival motor neuron 1 (SMN1) gene.

The investigators will conduct a systematic review of the contents and activities collected via a comprehensive case report form. Patients who fulfilled diagnostic criteria for SMA type 1 will be reviewed retrospectively.

Conditions

• Natural History of Type 1 Spinal Muscular Atrophy (SMA)

Sponsors & Collaborators

• Biogen

  collaborator INDUSTRY

• Taipei Medical University WanFang Hospital

  collaborator OTHER

• Taipei Veterans General Hospital, Taiwan

  collaborator OTHER_GOV

• Mackay Memorial Hospital

  collaborator OTHER

• Chang Gung Memorial Hospital

  collaborator OTHER

• China Medical University Hospital

  collaborator OTHER

• Chung Shan Medical University

  collaborator OTHER

• Changhua Christian Hospital

  collaborator OTHER

• Taichung Veterans General Hospital

  collaborator OTHER

• Chi Mei Medical Hospital

  collaborator OTHER

• Cathay General Hospital

  collaborator OTHER

• Shin Kong Wu Ho-Su Memorial Hospital

  collaborator OTHER

• Kaohsiung Veterans General Hospital.

  collaborator OTHER

• National Cheng-Kung University Hospital

  collaborator OTHER

• Buddhist Tzu Chi General Hospital

  collaborator OTHER

• Kaohsiung Medical University

  collaborator OTHER

• Taipei Medical University Shuang Ho Hospital

  collaborator OTHER

• National Taiwan University Hospital

  collaborator OTHER

• Taipei Medical University Hospital

  collaborator OTHER

• Kaohsiung Medical University Chung-Ho Memorial Hospital

  lead OTHER

Eligibility

Max Age

36 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2015-06-30

Primary Completion

2015-12-31

Completion

2015-12-31