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Carotenoid Absorption and Metabolism From Green-leafy Vegetable Matrices

NCT02450227 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 22

Last updated 2016-03-22

No results posted yet for this study

Summary

Absorption and metabolism of carotenoids from two types of spinach preparations will be investigated in two study groups, short bowel/ileostomy and healthy, respectively.

The study will be conducted as a randomised, controlled, 2-way crossover study in 24 participants (12 in each group), randomized to two sequences (1-2, 2-1) of interventions with a more and a less bio-accessible spinach preparation. The serum, chylomicron and fecal/effluent levels of lutein and beta-carotene will be determined.

Conditions

  • Ileostomy; Functional Disturbance
  • Healthy

Interventions

DIETARY_SUPPLEMENT

Spinach - Whole leaf (10 mg lutein)

Identical spinach meals processed in two different ways by Frigodan, served alone or together with habitual diet

DIETARY_SUPPLEMENT

Spinach - Minced (10 mg/lutein)

Identical spinach meals processed in two different ways by Frigodan, served alone or together with habitual diet

Sponsors & Collaborators

  • Agroscope Liebefeld-Posieux Research Station ALP

    collaborator OTHER

  • Rigshospitalet, Denmark

    collaborator OTHER

  • Herta Messerli Stiftung

    collaborator UNKNOWN

  • Glostrup University Hospital, Copenhagen

    collaborator OTHER

  • University of Copenhagen

    lead OTHER

Principal Investigators

  • Lars O Dragsted, PhD · University of Copenhagen

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-01-31
Primary Completion
2015-12-31
Completion
2015-12-31

Countries

  • Denmark

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02450227 on ClinicalTrials.gov