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An fMRI Study of Satiation in Healthy Volunteers.

NCT02298049 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2014-11-21

No results posted yet for this study

Summary

To our knowledge no study has assessed the effects of a meal on neural responses to food cues and compared this with a condition simulating natural inter-meal hunger levels. This is important, as the existing literature often compares the effect of fasting to satiation, which may not reflect typical appetite processes. Thus, the purpose of this research was to examine the effect of a satiating lunch compared to a normal pre-meal state on blood oxygen level dependent (BOLD) activity in the human brain, as measured using functional magnetic resonance imaging (fMRI).

Conditions

  • Appetite

Interventions

OTHER

Satiated / Pre-meal

All participants were scanned before and after not being fed (pre-meal), and before and after being given a satiating lunch (satiated).

DEVICE

MRI

Sponsors & Collaborators

  • University of Oxford

    collaborator OTHER

  • University of Birmingham

    lead OTHER

Principal Investigators

  • Jason M Thomas, MRes · University of Birmingham

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2010-07-31
Primary Completion
2010-12-31
Completion
2010-12-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02298049 on ClinicalTrials.gov