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Brain Activation During Accommodation to Painful Stimulation With FMRI

NCT01242540 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 15

Last updated 2017-06-26

No results posted yet for this study

Summary

Blood oxygen level dependant (BOLD) functional magnetic resonance imaging (FMRI) investigations of pain have provided substantial insight into the workings of the human brain. To date, however, the vast majority of studies have dealt with short painful stimulations. This work will expand the investigators knowledge of how longer stimulations are processed by comparing the activation pattern from a two minute painful stimulation with that of an 30-second painful stimulus. The investigators hypothesis that accommodation to the longer stimulation will be evident by either decreases in signal intensity in brain areas known to process pain, or by increasing activity in brain areas thought to be responsible for the modulation of painful perception.

Conditions

Sponsors & Collaborators

  • University of Pittsburgh

    lead OTHER

Principal Investigators

  • James W Ibinson, MD, PhD · University of Pittsburgh

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2010-11-30
Primary Completion
2011-06-30
Completion
2016-10-31

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01242540 on ClinicalTrials.gov