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MRI Neurofeedback and Brain Circuits Related to Motivation in Healthy Participants

NCT05929898 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 190

Last updated 2025-08-22

No results posted yet for this study

Summary

The purpose of this research study is to understand how healthy individuals self-regulate motivation by observing brain activity using magnetic resonance imaging (MRI).

Conditions

  • Motivation
  • Memory
  • Self-regulation

Interventions

BEHAVIORAL

Ventral tegmental area of dopaminergic midbrain (VTA) fMRI neurofeedback

fMRI neurofeedback training of sustained midbrain/VTA activation via motivational imagery.

Sponsors & Collaborators

  • National Institute of Mental Health (NIMH)

    collaborator NIH

  • Duke University

    lead OTHER

Principal Investigators

  • R. Alison Adock, MD, PhD · Duke University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-07-30
Primary Completion
2026-09-08
Completion
2026-09-09

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05929898 on ClinicalTrials.gov