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Brain Mechanisms of Overeating in Children

NCT03341247 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 254

Last updated 2024-01-03

No results posted yet for this study

Summary

The proposed research will follow healthy weight children who vary by family risk for obesity to identify the neurobiological and appetitive traits that are implicated in overeating and weight gain during the critical pre-adolescent period. The investigator's central hypothesis is that increased intake from large portions of energy dense foods is due in part to reduced activity in brain regions implicated in inhibitory control and decision making, combined with increased activity in reward processing pathways. To test this hypothesis, the investigators will recruit 120 healthy weight children, aged 7-8 years, at two levels of obesity risk (i.e., 60 high-risk and 60 low-risk) based on parent weight status. This will result in 240 participants: 120 children and their parents.

Conditions

  • Pediatric Obesity
  • Inhibition
  • Decision Making
  • fMRI

Sponsors & Collaborators

  • Penn State University

    lead OTHER

Principal Investigators

  • Kathleen L Keller, Ph.D. · Penn State University

Eligibility

Min Age
7 Years
Max Age
8 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-01-31
Primary Completion
2023-06-20
Completion
2023-06-20

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03341247 on ClinicalTrials.gov