MedTrace Logo

Planetary Habitat Simulation: Nutrition Studies

NCT02293772 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 14

Last updated 2019-03-15

No results posted yet for this study

Summary

A loss of body weight has been documented in lowland-living individuals when exposed to hypoxic environments, such as at high altitude, or under laboratory conditions. A reduction in appetite and energy intake has also been reported during conditions of microgravity, such as during space flight. Fourteen normal or over-weight men, who are otherwise healthy, will undergo 3x 21-day interventions; normobaric normoxic bed rest (NBR; FiO2=21%), normobaric hypoxic ambulatory confinement (HAMB; FiO2=14%; \~4000 m simulated altitude), and normobaric hypoxic bed rest (HBR; FiO2=14%). The effects of hypoxia and bedrest on appetite and its hormonal control will be assessed before and at day 17 of each intervention using a mixed meal tolerance test.

Conditions

Interventions

OTHER

Hypoxic ambulatory

21 days confinement in normobaric hypoxic (FiO2 = 14%) environment

OTHER

Hypoxic Bedrest

21 days supine bedrest in normobaric hypoxic (FiO2 = 14%) environment

OTHER

Normoxic Bedrest

21 days supine bedrest in normobaric normoxic (FiO2 = 21%) environment

Sponsors & Collaborators

  • Jozef Stefan Institute

    collaborator OTHER

  • KTH Royal Institute of Technology

    collaborator OTHER

  • European Commission

    collaborator OTHER

  • University of Nottingham

    lead OTHER

Principal Investigators

  • Igor Mekjavic, PhD · Jozef Stefan Institute

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
25 Years
Max Age
45 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-03-31
Primary Completion
2013-11-30
Completion
2014-10-31

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02293772 on ClinicalTrials.gov