Effects of Different Aerobic Exercise Programs With Nutritional Interventions in Hypertensive and Overweight People

Summary

Obesity and arterial hypertension (HTN) frequently coexist in the same patient. Moreover, the concept that obesity and HTN can be additive in terms of cardiovascular rist is widely accepted. Yet, clinical decision-making in obese patients is complicated by a surprising lack of evidence on the relative importance of obesity and HTN treatment and its efficacy and safety. Lifestyle interventions are the mainstay of obesity management programs and are also advocated in the prevention and treatment of HTN. Physical exercise and diet are recommended to prevent and control obesity and HTN. Aerobic exercise is firmly established as an effective measure for lowering blood pressure and reducing cardiovascular risk. However, there is no agreement about the optimal dose of frequency, intensity, duration and type of exercise. Therefore, the aims of the study are: 1) to assess the changes in selected parameters of blood pressure, cardiorespiratory fitness, body composition and biological markers brought about by a period of 16-week of different aerobic exercise programs with hypocaloric diet for overweight or obesity and primary hypertensive adults, and 2) to examine the effect of six months detraining subsequent to intervention. Secondary objectives are to examine the additional effect of the intervention on physical activity behavior and health-related quality of life.

Conditions

• Hypertension
• Overweight
• Sedentary

Interventions

BEHAVIORAL

DIET

Lifestyle intervention through hypocaloric diet

BEHAVIORAL

DIET & MODERATE CONTINUOUS TRAINING

Lifestyle intervention through hypocaloric diet and exercise at moderate intensity (60-80%peakHR) continuous mode, and high volume (45 min).

BEHAVIORAL

DIET & HIGH VOLUME HIIT

Lifestyle intervention through hypocaloric diet and exercise at high intensity (80-95%peakHR) interval mode, and high volume (45 min).

BEHAVIORAL

DIET & LOW VOLUME HIIT

Lifestyle intervention through diet and exercise at high intensity (80-95%peakHR) interval mode, and low volume (20 min).

Sponsors & Collaborators

• IMQ-Igualatorio Médico Quirúrgico, Vitoria-Gasteiz (Araba/Álava)

  collaborator UNKNOWN

• Servicios Tecnológicos de Tecnalia

  collaborator UNKNOWN

• Hospital Comarcal Santiago Apostol, Miranda de Ebro (Burgos)

  collaborator UNKNOWN

• University of the Basque Country (UPV/EHU)

  lead OTHER

Principal Investigators

• SARA MALDONADO-MARTIN, PhD · University of the Basque Country (UPV/EHU)

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

70 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2015-01-31

Primary Completion

2016-06-30

Completion

2017-01-31

Countries

• Spain

Study Locations