AM vs PM Exercise Training
NCT06042439 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 79
Last updated 2025-09-25
Summary
The treatment of high blood pressure, or hypertension, is multifaceted and can include pharmacological therapies (i.e., medications) and lifestyle modifications such as physical activity. Chronotherapy, which describes timing of a treatment with the body's daily rhythms, has recently been used with hypertension medications and has been shown to be effective at lowering blood pressure and reducing the risk of cardiovascular disease events. Specifically, taking medications in the evening was shown to be more effective than morning medication routines. Little information is available about the effectiveness of chronotherapy combined with exercise (i.e., planned physical activity) interventions in older adults with hypertension. The purpose of this study is to examine how exercise training performed in the morning and early evening affects blood pressure and other measures of blood vessel health in postmenopausal females with hypertension.
Conditions
Interventions
- BEHAVIORAL
-
6 weeks of exercise training (Pre-training)
handgrip and treadmill walking 4 days per week
- BEHAVIORAL
-
6 weeks of exercise training (Post-training)
handgrip and treadmill walking 4 days per week
Sponsors & Collaborators
-
National Heart, Lung, and Blood Institute (NHLBI)
collaborator NIH - lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 55 Years
- Max Age
- 80 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-06-11
- Primary Completion
- 2027-07-01
- Completion
- 2027-07-01
Countries
- United States
Study Locations
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