Metabolic Fuels Study

Summary

This study will evaluate a potential physiologic mechanism underlying the effects of dietary composition on control of body weight

Conditions

• Obesity

Interventions

BEHAVIORAL

Low carbohydrate diet

Composition (by proportion of calories) : 15% carbohydrate, 65% fat, 20% protein

BEHAVIORAL

Moderate carbohydrate diet

Feeding study. Composition (by proportion of calories): 40% carbohydrate, 40% fat, 20% protein

BEHAVIORAL

High carbohydrate diet

Feeding study. Composition (by proportion of calories): 60% carbohydrate, 20% fat, 20% protein

Sponsors & Collaborators

• Framingham State University

  collaborator OTHER

• Brigham and Women's Hospital

  collaborator OTHER

• Boston Medical Center

  collaborator OTHER

• Nutrition Science Initiative

  collaborator OTHER

• New Balance Foundation

  collaborator OTHER

• Boston Children's Hospital

  lead OTHER

Principal Investigators

• Kim Shams, MD · Boston Children's Hospital

• David s Ludwig, MD, PhD · Boston Children's Hospital

• Cara B Ebbeling, PhD · Boston Children's Hospital

Study Design

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

65 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2014-10-31

Primary Completion

2016-05-31

Completion

2017-05-31

Countries

• United States

Study Locations