The largest CAR-T trial for pediatric solid tumors has opened in the US and UK, enrolling up to 60 young patients across four sites. The NexTGen study targets relapsed or refractory cancers and focuses first on safety and feasibility.
New treatments for rare pediatric neurological conditions show promise, with zorevunersen reducing seizures in Dravet syndrome patients and an SMA therapy under FDA review following stem cell research breakthroughs.
March of Dimes awarded the 2026 Richard B Johnston Jr, MD Prize to hematologist Leonard Zon for pioneering zebrafish research that illuminated blood development in embryos and led to breakthrough treatments for genetic blood disorders in children.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07706140 |
Observational Data Collection for Blood Hemoglobin Algorithm Validation in Pediatrics |
NOT_YET_RECRUITING | |
| NCT07677865 |
GLP-1 Receptor Agonists and Alzheimer's Disease: A Multi-National Target Trial Emulation |
COMPLETED | |
| NCT07676474 |
Continuous Wireless Ultrasound to Monitor Fetal Health |
NOT_YET_RECRUITING | |
| NCT07674043 |
MY01 Pressure Monitoring in Adolescent Tibia Fractures |
NOT_YET_RECRUITING | NA |
| NCT07650643 |
EEG Biomarkers for ADHD Stimulant Treatment |
NOT_YET_RECRUITING | PHASE4 |
| NCT07607821 |
Validation of ECG-Based Ventricular Arrhythmia Localization Algorithms in Patients With Repaired Tetralogy of Fallot |
NOT_YET_RECRUITING | NA |
| NCT07601581 |
A Trial to Determine People's Explicit vs. Implicit Preferences for Gender-inclusive Sexual and Reproductive Health Content |
COMPLETED | NA |
| NCT07571811 |
Pharmacokinetic and Pharmacodynamic Investigations of Fetal Anesthesia During Maternal Fetal Surgery |
NOT_YET_RECRUITING | |
| NCT07549646 |
24VA021; VATCH Trametinib for Ras/MAPK Pathway VAs |
ACTIVE_NOT_RECRUITING | PHASE2 |
| NCT07545005 |
Impact of a Produce Prescription Program and Nutrition Education Intervention on Cardiovascular Health in Youth |
NOT_YET_RECRUITING | NA |
