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Oral Curcumin Supplementation in Middle-Aged and Older Adults Improves Vascular Function

NCT01968564 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 118

Last updated 2017-03-20

No results posted yet for this study

Summary

The proposed study will assess the ability of curcumin, the active ingredient in the Indian spice tumeric, to improve the function of arteries with age. Overall, the proposed research project has the long-term potential to influence clinical practice guidelines by establishing a novel, easy to deliver, cost-effective therapy for treating age-associated arterial dysfunction and reducing the risk of cardiovascular disease with age.

Conditions

  • Vascular Aging

Interventions

DRUG

Placebo pill

sugar and other inert substances

DRUG

High-dose curcumin pill

2000mg curcumin pill/day

DRUG

Low-dose curcumin pill

500mg curcumin pill/day

Sponsors & Collaborators

  • University of Colorado, Boulder

    lead OTHER

Principal Investigators

  • Jessica Santos-Parker, MS · University of Colorado, Boulder

  • Douglas Seals, PhD · University of Colorado, Boulder

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
45 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-06-30
Primary Completion
2017-06-30
Completion
2017-06-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01968564 on ClinicalTrials.gov