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Curcumin and Vascular and Cognitive Function in Patients With Chronic Kidney Disease

NCT03223883 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 94

Last updated 2024-10-08

Study results available
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Summary

The proposed research is clinical study evaluating the therapeutic benefits of curcumin on vascular function in patients with chronic kidney disease (CKD). The study aims to establish that curcumin will improve endothelial function and reduce large artery stiffness by reducing oxidative stress and in conjunction with lowering markers of inflammation and oxidative stress. In addition, the study will evaluate the potential benefit of curcumin on cognitive function in patients with CKD.

Conditions

Interventions

DRUG

Curcumin

Oral supplement for 12 months

OTHER

Placebo

Oral placebo for 12 months

Sponsors & Collaborators

  • University of Colorado, Boulder

    collaborator OTHER

  • Stanford University

    collaborator OTHER

  • University of Colorado, Denver

    collaborator OTHER

  • Diana Jalal

    lead OTHER

Principal Investigators

  • Diana Jalal · University of Iowa

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
45 Years
Max Age
74 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-06-01
Primary Completion
2023-01-25
Completion
2023-01-25
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03223883 on ClinicalTrials.gov