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Relevance of the Ethanol Dose in the Generation of Endogenous Hydroxytyrosol

NCT01788670 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2013-02-11

No results posted yet for this study

Summary

Health benefits for humans derived from low dose intake of ethanol could partially be explained by its interaction with dopamine (DA) oxidative metabolism. Ethanol is expected to induce an increase in the formation of a DA minor metabolite: DOPET (hydroxytyrosol). Hydroxytyrosol is one of the most potent antioxidants present in Mediterranean Diet. The study is aimed at establishing the contribution of ethanol on hydroxytyrosol formation.

Conditions

  • Contribution of Ethanol on Hydroxytyrosol Formation

Interventions

DIETARY_SUPPLEMENT

Ethanol

OTHER

Water

Sponsors & Collaborators

  • Fundacion IMIM

    collaborator OTHER

  • Parc de Salut Mar

    lead OTHER

Principal Investigators

  • Magí Farré, MD, PhD · Parc de Salut Mar

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-05-31
Primary Completion
2010-06-30
Completion
2010-06-30

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01788670 on ClinicalTrials.gov