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Effect of Lidocaine Sprayed on Hemodynamics During Endotracheal Intubation

NCT01737437 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2012-11-29

No results posted yet for this study

Summary

A previous study demonstrated topical lidocaine spray on the larynx and the trachea is effective in reducing hemodynamic response to laryngoscopy and endotracheal intubation. In clinical practice, blind oropharyngeal application of lidocaine without aiding direct laryngoscopy can not assured that sprayed lidocaine effectively reaches the larynx and trachea. Therefore, direct laryngoscopy should be necessary to reach topical lidocaine to correct sites. Unfortunately, direct laryngoscopy itself can affect hemodynamics during spraying lidocaine. In this study, we will investigate an effect of lidocaine sprayed on direct laryngoscopy and the tracheal mucosa on hemodynamic change throughout intubation.

Conditions

  • Neurosurgical Patients

Interventions

DRUG

group C

0.9% normal saline was applied to trachea and laryngoscope blade

DRUG

group L

10% Lidocaine was applied to the laryngoscope blade and 0.9% normal saline was applied to the trachea.

DRUG

group V

0.9% normal saline was applied to the laryngoscope blade and 10% Lidocaine was applied on trachea.

DRUG

group LV

10% Lidocaine was applied on laryngoscope blade and trachea.

Sponsors & Collaborators

  • Seoul National University Hospital

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-10-31
Primary Completion
2013-01-31
Completion
2013-01-31

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01737437 on ClinicalTrials.gov