MedTrace Logo

The Effect of Local Anesthetic Techniques on Hemodynamic Response and Postoperative Sore Throat in Double-Lumen Tubes

NCT06705595 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2025-01-13

No results posted yet for this study

Summary

This clinical trial aims to determine if different local anesthetic application techniques can reduce postoperative sore throat (POST) and manage hemodynamic responses in adult patients undergoing elective thoracic surgery with double-lumen intubation. The main questions it aims to answer are:

* Does inhaled lidocaine or lidocaine applied to the double-lumen tube reduce the incidence and severity of POST?
* How do these anesthetic techniques impact hemodynamic stability during surgery?

Researchers will compare three groups-those receiving inhaled lidocaine, lidocaine applied to the tube, and a saline control group-to see if these methods differ in effectiveness.

Participants will:

* Undergo standard preoperative assessment and provide informed consent
* Be randomly assigned to receive either inhaled lidocaine, lidocaine applied to the tube, or saline
* Have sore throat scores and hemodynamic data recorded at specific intervals after surgery

Conditions

  • Anesthesia, Local
  • Intubation, Intratracheal
  • Double-lumen Tube
  • Sore Throat
  • Lidocaine Spray

Interventions

DRUG

Tracheo-Spray

Participants will receive 2 ml of 10% lidocaine delivered via a Tracheo-Spray device to the tracheal mucosa before anesthesia induction.

DRUG

Lidocaine Spray on DLT

Before intubation, participants will receive 10% lidocaine spray applied to the distal surface and cuffs of the double-lumen tube (DLT).

DRUG

Saline (Placebo)

Before intubation, participants will receive 1 ml of 0.9% saline applied to the distal surface and cuffs of the double-lumen tube (DLT).

Sponsors & Collaborators

  • V.K.V. American Hospital, Istanbul

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-11-06
Primary Completion
2024-12-06
Completion
2024-12-12

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06705595 on ClinicalTrials.gov