MedTrace Logo

Effect of Age and Weight Loss on Inflammation and Iron Homeostasis

NCT01636635 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 44

Last updated 2015-11-16

No results posted yet for this study

Summary

The purpose of this study is to evaluate the effect of aging and weight loss on iron status and immune response in obese women. Iron deficiency and immune impairment are two of the numerous complications of obesity. The central hypothesis is that obesity-induced inflammation causes lower iron status through decreased iron absorption and availability in young and older obese women. Furthermore, the investigators hypothesize that this can be corrected with weight loss in both young and older obese women.

Conditions

Interventions

OTHER

Calorie Restriction

Intervention consists of a calorically restricted diet regime designed and administered at the Weight and Wellness Center at Tufts University

Sponsors & Collaborators

  • Tufts University

    lead OTHER

Principal Investigators

  • Simin N Meydani, DVM, PhD · Tufts University

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-03-31
Primary Completion
2013-11-30
Completion
2013-11-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01636635 on ClinicalTrials.gov