Cruciferous Vegetable Intake and Histone Status in Screening Colonoscopy Patients

NCT01344330 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 108

Last updated 2020-12-19

No results posted yet for this study

Summary

This research study will assess cruciferous vegetable intake in patients presenting for screening colonoscopy and correlate intake with histone status and histone deacetylace (HDAC) expression in tissue biopsy specimens and peripheral blood mononuclear cells (PBMCs). The investigators will also measure sulforaphane (SFN) metabolites in blood as a biomarker of cruciferous vegetable intake.

Conditions

Sponsors & Collaborators

  • Oregon Health and Science University

    collaborator OTHER
  • National Cancer Institute (NCI)

    collaborator NIH
  • Texas A&M University

    lead OTHER

Principal Investigators

  • Rod Dashwood, PhD · Oregon State University

Eligibility

Min Age
50 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-01-31
Primary Completion
2017-12-31
Completion
2017-12-31

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01344330 on ClinicalTrials.gov