DNA Changes That Affect Vitamin D Metabolism in Patients With Colorectal Cancer Receiving Vitamin D Supplements
NCT00550563 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2017-04-04
Summary
RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
PURPOSE: This clinical trial is studying changes in DNA that affect vitamin D metabolism in patients with colorectal cancer receiving vitamin D supplements.
Conditions
Interventions
- DIETARY_SUPPLEMENT
-
cholecalciferol
Oral
- GENETIC
-
polymerase chain reaction
companion study
- GENETIC
-
polymorphism analysis
companion study
- GENETIC
-
protein expression analysis
companion study
- GENETIC
-
reverse transcriptase-polymerase chain reaction
companion study
- GENETIC
-
western blotting
companion study
- OTHER
-
high performance liquid chromatography
companion study
- OTHER
-
laboratory biomarker analysis
companion study
- OTHER
-
pharmacological study
companion study
- PROCEDURE
-
adjuvant therapy
Additional therapy
- PROCEDURE
-
immunoscintigraphy
additional testing
Sponsors & Collaborators
-
Roswell Park Cancer Institute
lead OTHER
Principal Investigators
-
Marwan Fakih, MD · Roswell Park Cancer Institute
Study Design
- Allocation
- NA
- Purpose
- SUPPORTIVE_CARE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 120 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-08-31
- Primary Completion
- 2009-04-30
- Completion
- 2010-07-31
Countries
- United States
Study Locations
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