Also known as: UCLA
The FDA approved Tzield for stage 3 type 1 diabetes, and the therapy was given to children in Canada for the first time. Research also advanced on engineered islets and stem-cell treatments.
AI is transforming cardiovascular medicine: $1.4B+ in investments, a new cardiac biomarker sensor, and stroke-imaging software in 2,500+ hospitals. FDA, EMA, and PMDA are opening clearer regulatory pathways.
UCLA-led research finds telemedicine has not significantly increased healthcare visits or costs across all payer types from 2019-2023, published in JAMA Network Open. A separate study of Medicare patients reveals nearly half of telehealth visits are for non-mental health conditions, particularly chronic diseases like diabetes and high blood pressure. Both findings address questions about telehealth's role and impact since the COVID-19 pandemic.
A phase II trial of TAK-007 CAR-NK therapy in R/R B-cell NHL showed a 60.9% overall response rate. Preclinical CAR-NKT therapy eliminated endometrial tumors in models. Optimized costimulatory domains (2B4-DAP12) boosted CAR-NK tumor killing.
New research shows AI can predict heart disease risk from breast arterial calcification on mammograms, while the BRAIx tool helps assess breast cancer risk. A $16 million U.S. trial, PRISM, will evaluate AI-assisted reading of screening mammograms.
Researchers developed a lipid nanoparticle gene-editing approach that inserted a full CFTR gene into airway cells and restored 88% to 100% of normal channel function in a cystic fibrosis lab model.
Three new CRISPR-based therapies show promise for treating heart failure through mitochondrial enhancement, cystic fibrosis via lipid nanoparticle gene insertion, and elevated cholesterol with single-dose gene editing targeting ANGPTL3.
UCLA scientists developed a lipid nanoparticle-based gene editing system that successfully inserts a full-length healthy CFTR gene into human airway cells, offering potential treatment for cystic fibrosis patients unresponsive to current therapies.
A UCLA clinical trial found that adding immunotherapy to chemotherapy before surgery is safe for borderline-resectable pancreatic cancer patients, with a subset experiencing deep, durable responses including complete tumor regression.
UCLA researchers developed lipid nanoparticle-based gene editing that inserts a complete CFTR gene into human airway cells, restoring up to 100% of normal channel function in cystic fibrosis laboratory models without viral vectors.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07780708 |
Measurement and Determinants of Diet Quality in Older Adults |
RECRUITING | |
| NCT07780162 |
Wearable Sensor for Early Detection and Monitoring of Cognitive Decline |
NOT_YET_RECRUITING | |
| NCT07761728 |
The FLARE (Flurpiridaz vs. Rubidium Evaluation) Trial |
ENROLLING_BY_INVITATION | |
| NCT07756567 |
Developing a Recovery-Oriented Suicide Prevention Program for Young People at Clinical High Risk for Psychosis |
NOT_YET_RECRUITING | NA |
| NCT07730177 |
Challenge Trial of PfSPZ-LARC2 Vaccine in Burkina Faso |
NOT_YET_RECRUITING | PHASE1 |
| NCT07715591 |
Randomized Controlled Trial of the STEIN Protocol: A Neuroplastic Pain Education and Guided Breathing Intervention During Awake Cataract Surgery |
RECRUITING | NA |
| NCT07706803 |
Screening For Social Determinants Of Health In Routine Diabetes Care |
NOT_YET_RECRUITING | NA |
| NCT07706634 |
Care Disengagement Prevention in PLWH in Indonesia |
RECRUITING | NA |
| NCT07699107 |
Adalimumab Dose Adjustment for Pediatric Uveitis Treatment Trial |
NOT_YET_RECRUITING | PHASE4 |
| NCT07686614 |
Telephone-Based Care Coordination for Services Addressing Childhood Adversity |
NOT_YET_RECRUITING | NA |
