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The Acute Effect of Beetroot Juice in Normal and Hypertensive Subjects

NCT01236872 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 15

Last updated 2011-08-08

No results posted yet for this study

Summary

Inorganic nitrate can be converted to nitrite and thence nitric oxide in humans. Nitric oxide is normally produced by the inner lining of blood vessels and helps keep blood vessels open and therefore blood pressure lower. In subjects with high blood pressure, the inner lining of the blood vessels does not function adequately. The investigators wish to investigate whether elevating systemic levels of inorganic nitrate (through provision of dietary nitrate-rich vegetables) can elevate levels of nitrate/nitrite in hypertensive subjects, and whether this has a beneficial effect on blood pressure.

Conditions

Interventions

DIETARY_SUPPLEMENT

Beetroot juice

250ml once of beetroot juice

DIETARY_SUPPLEMENT

Water

250ml once of low-nitrate mineral water

Sponsors & Collaborators

  • University College, London

    collaborator OTHER

  • Queen Mary University of London

    lead OTHER

Principal Investigators

  • Amrita Ahluwalia · QMUL

Study Design

Allocation
RANDOMIZED
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-12-31
Primary Completion
2010-12-31
Completion
2010-12-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01236872 on ClinicalTrials.gov